Us3749722a method for preparing amides of trimellitic. Exam 3 problems ch 20 and 21 carboxylic acids and derivatives. Date hs code description origin country port of discharge unit quantity value inr per unit inr nov 21 2016. The last traces of acetic acid are removed under vacuum and after cooling to about 5060 c, otoluidine 10 grams is added in portions. Costic anhydride article pdf available in acta crystallographica section e structure reports online 66pt 3. The following 27 files are in this category, out of 27 total. Acetic anhydride can be made by passing vaporizing glacial acetic acid and passing it through a small furnace to increase temperature to around 900 deg f. Isatoic anhydride is a hetero bicyclic aromatic compound with diketone at 2 and 4 positions and additional one oxygen atom in the ring system. Esters and anhydride reactions ester reactions amide and nitrile reactions amides and nitrile reactions 2 problem set 1 draw some products.
The extraction efficiency was evaluated over the range of 19. Trimellitic anhydride an overview sciencedirect topics. This reaction is expected to be slow, but can become vigorous if local heating accelerates it. Click, drag, and drop to reorder files or press delete to remove any content you dont want. Carboxylic acid anhydrides exhibit symmetrical and asymmetric co 2 stretching vibration v ip co 2 and v op co 2, respectively. Isatoic anhydride is a very useful intermediate in industry for making things and stuff. Sigmaaldrich offers a number of isatoic anhydride products. A carboxylic acid such as ethanoic acid has the structure. Phthalic anhydride is an important chemical intermediate in the plastics industry from which are derived numerous phthalate esters that function as plasticizers in synthetic resins. Preparation of isatoic anhydride from phthalimide article pdf available in organic preparations and procedures international 143. Functional group is an acid anhydride therefore suffix oic anhydride hydrocarbon structure is an alkane therefore an. Isatoic anhydride is an organic compound derived from anthranilic acid. Chemistry a compound that has been formed from another compound by dehydration 2. Alternatively, the reaction between the acid chloride and a salt of acetic acid e.
Acetic anhydride 3506 wikisource, the free online library. These can range from pesticides to muscle relaxant medications. Alcoholysis proceeds similarly, affording the ester. Resins produced by the condensation reaction of trimellitic anhydride occ 6 h 2 c 2 o 3 and various aromatic diamines.
Anthranilic acid 10 grams is dissolved in acetic anhydride 20 ml and the temperature raised progressively to 190200 c at which temperature distillation takes place. Hydrolysis gives carbon dioxide and anthranilic acid. Date hs code description origin country port of discharge unit quantity value inr per unit inr nov 22 2016. A typical base anhydride reaction is the reaction of calcium oxide. Maleic anhydride process feautures the maleic anhydride process offered by conser is a gas phase catalytic oxidation process using normal butane as feedstock. Anhydrides definition of anhydrides by medical dictionary. Incompatible with strong oxidizing agents, strong acids or strong bases.
Trimellitic anhydride 5036 wikisource, the free online. As the vapors pass through the furnace coils a catalyst such as diammonium phosphate dap is injected. It finds application in personal care products like hair. Examples of inorganic anhydrides are sulfur trioxide, so3, which is derived from sulfuric acid, and calcium oxide. Anhydride, any chemical compound obtained, either in practice or in principle, by the elimination of water from another compound. Quinolines from the cyclocondensation of isatoic anhydride. Massey, in permeability properties of plastics and elastomers second edition, 2003. Acetic anhydride is used as an intermediate to produce a variety of acylated products. It is also used as lubricating oil additives, dispersants, artificial sweeteners, flavor enhancements, floor polishes and corrosion inhibitors.
In step 2, the anhydride electrophiles are reacted with the sodium enolate of ethyl acetoacetate, generated from sodium hydroxide, in warm n,n dimethylacetamide resulting in the formation of substituted quinolines. Safety of maleic acidmaleic anhydride based on efsas information, a tdi tolerable daily intake of 0. Calculate the concentration of trimellitic anhydride, c mgm 3 in the air volume sampled, vl. A white solid, it is prepared by reaction of anthranilic acid with phosgene.
Maleic anhydride is used in the preparation of unsaturated polyester resins, 4butanediol, fumairc acid, tetrahydrofuran and gammabutyrolactone. Method 3506, issue 2, dated 15 august 1994 page 4 of 4 references. Isatoic anhydride definition is a highmelting dicarboxylic acid anhydride c8h5no3 made by oxidation of isatin or by reaction of anthranilic acid with phosgene. Product name, description empirical formula hill notation. Its major use is in the manufacture of cellulose acetates. Maleic anhydride is incompatible with alkali metals and amines, and will react violently with bases. Nalkylation of isatoic anhydrides adapted from that reported by hardtmann et al 3 nah 2. As the name indicates, an acid anhydride is a compound that is related to an acid by the loss of water. Isatoic anhydride definition of isatoic anhydride by. Anhydride definition of anhydride by the free dictionary.
It has a lactam structure which is an important part of antibiotics, such as penicillin and textiles. It, a cyclic ester, is a versatile intermediate used for the manufacture of target materials. Trimellitic anhydride reacts exothermically with water. You can merge pdfs or a mix of pdf documents and other files. This file is licensed under the creative commons attributionshare alike 4. Department of health, education, and welfare, publ. The v ip co 2 mode has stronger infrared ir band intensity than v op co 2. Safety data sheet per osha hazcom 2012 usc upstate. Open chain saturated aliphatic anhydrides exhibit v ip co 2 in the range 18151825 cm1 and v op co 2 in the range 17451755 cm1. Phthalic anhydride itself is used as a monomer for synthetic resins such as glyptal, the alkyd resins, and the polyester resins. While the addition of a nitro group yields desirable activation of the reagent, it also leads to poorer water solubility. Contact with strong oxidizers may present a fire or explosion hazard.
Many of its industrial uses depend on the reactivity of the anhydride group. The following procedure starts from phathlic acid, undergoing thermal rearrangement to yield phthalic anhydride. Us2962504a us2962504da us2962504a us 2962504 a us2962504 a us 2962504a us 2962504d a us2962504d a us 2962504da us 2962504 a us2962504 a us 2962504a authority us united states prior art keywords acetic acid glacial acetic solution dichloromaleimide anhydride prior art date 19601129 legal status the legal status is an assumption and is not. An acid anhydride is a compound that has two acyl groups bonded to the same oxygen atom. Use this link for bookmarking this species for future reference. Pdf preparation of isatoic anhydride from phthalimide. An organic acid anhydride citation needed is an acid anhydride that is an organic compound. Contamination of maleic anhydride modified starch in food. Predicted data is generated using the us environmental protection agencys episuite. How to merge pdfs and combine pdf files adobe acrobat dc. If you took two ethanoic acid molecules and removed a molecule of water between them you would get the acid anhydride, ethanoic anhydride old name. Niosh manual of analytical methods nmam, fourth edition, 81594 acetic anhydride.
Maleic anhydride 100 108316 ingredient name % cas number there are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases. A chemical compound formed from another, often an acid, by the removal of water. Thanks to an advanced reaction system integrated with a patented process of recovery and purification, the technology can be regarded as highly. Click add files and select the files you want to include in your pdf. Chemistry a compound that forms an acid or base when added to water 3. To the stirred mixture at 20 c was added isatoic anhydride 1a. There is no warranty of accuracy or completeness of any information contained herein. A common type of organic acid anhydride is a carboxylic anhydride, where the parent acid is a carboxylic acid, the formula of the anhydride being rco 2 o.
1107 1074 1436 371 556 1443 607 450 1215 1496 219 1345 1058 1039 1079 1134 1002 598 1272 212 769 1132 1291 402 227 701 461 530 122 326 1300 678 914 926 818 1322 776